Цитаты из книги Outlive: A arte e a ciência de viver mais e melhor

This would seem to be a relatively straightforward task: sequence the genomes of a few thousand centenarians and see which individual genes or gene variants stand out as being more prevalent among this population than in the general population. Those would be your candidate genes. But when researchers did this, examining…

This is part of why I place so much importance on taking a detailed family history from my patients: I need to know when your relatives died and why. What are your likely “icebergs,” genetically speaking?

Frenchwoman Jeanne Calment, who once joked, “I’ve only ever had one wrinkle, and I’m sitting on it.”

as the great philosopher Mike Tyson once put it, “Everyone has a plan until they get punched in the mouth.”

This means that we have delayed your death without significantly improving your quality of life—something at which Medicine 2.0 is quite adept. This is the Marginal Decade that most of us can expect, in our current system.

In Medicine 2.0, you are a passenger on the ship, being carried along somewhat passively. Medicine 3.0 demands much more from you, the patient: You must be well informed, medically literate to a reasonable degree, clear-eyed about your goals, and cognizant of the true nature of risk.

The trouble began with Hippocrates. Most people are familiar with the ancient Greek’s famous dictum: “First, do no harm.” It succinctly states the physician’s primary responsibility, which is to not kill our patients or do anything that might make their condition worse instead of better. Makes sense. There are only three…

In late 2007, after six months of round-the-clock work, we had a big meeting with the top brass of our client, a major US bank. Normally, my boss, as the senior partner on the project, would have handled the presentation. But instead he picked me. “Based on your previous career choice,” he said, “I suspect you are better…